Cardizem

Pronunciation: dil-TYE-a-zem
Generic Name: Diltiazem
Brand Name: Cardizem

Cardizem is used for:

Treating supraventricular tachycardia, a rhythm disturbance of the heart. It is also used for controlling heart rate response to other rhythm disturbances, specifically atrial fibrillation and atrial flutter. It may also be used for other conditions as determined by your doctor.

Cardizem is a calcium channel blocker. It works by slowing the electrical conduction in the heart, slowing heart rate, and/or normalizing heart rhythm.

Do NOT use Cardizem if:

• you are allergic to any ingredient in Cardizem


• you have certain heart problems (eg, sick sinus syndrome, second- or third-degree heart block) and do not have a pacemaker, or you have very low blood pressure


• you have atrial fibrillation or atrial flutter and a pre-excitation syndrome (extra conduction pathway in the heart), such as Wolff-Parkinson-White syndrome (WPW) or Lown-Ganong-Levine syndrome (LGL)


• you are receiving an injectable beta-blocker (eg, metoprolol) or erythromycin

Contact your doctor or health care provider right away if any of these apply to you.

Before using Cardizem:

Some medical conditions may interact with Cardizem. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have heart failure, a recent heart attack with lung congestion, heart block, a very slow heart rate, abnormal heart rhythm, or other heart problems


• if you have low blood pressure or kidney or liver disease


• if you are taking other medicines for high blood pressure or heart conditions

Some MEDICINES MAY INTERACT with Cardizem. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Antiarrhythmics (eg, amiodarone, dronedarone), cimetidine, clonidine, HIV protease inhibitors (eg, atazanavir, indinavir), or tricyclic antidepressants (eg, desipramine) because they may increase the risk of Cardizem's side effects, such as heart rhythm problems


• Benzodiazepines (eg, midazolam), beta-blockers (eg, metoprolol), buspirone, carbamazepine, cilostazol, cisapride, colchicine, corticosteroids (eg, prednisone), cyclosporine, digoxin, everolimus, fentanyl, HMG-CoA reductase inhibitors (eg, atorvastatin), hydantoins (eg, phenytoin), lurasidone, macrolide antibiotics (eg, erythromycin), macrolide immunomodulators (eg, tacrolimus), nifedipine, quinidine, ranolazine, theophylline, or vasopressin antagonists (eg, tolvaptan) because the risk of their side effects, some potentially life-threatening, may be increased by Cardizem


• Moricizine or rifamycins (eg, rifampin) because they may decrease Cardizem's effectiveness

This may not be a complete list of all interactions that may occur. Ask your health care provider if Cardizem may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Cardizem:

Use Cardizem as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Cardizem is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Cardizem at home, a health care provider will teach you how to use it. Be sure you understand how to use Cardizem. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.


• Do not use Cardizem if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.


• Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.


• If you miss a dose of Cardizem, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Cardizem.

Important safety information:

• Cardizem may cause dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use Cardizem with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Cardizem may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.


• Do NOT use more than the recommended dose or stop using Cardizem without checking with your doctor.


• Cardizem may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Cardizem. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.


• Tell your doctor or dentist that you take Cardizem before you receive any medical or dental care, emergency care, or surgery.


• Lab tests, including electrocardiogram (ECG), heart rate, and blood pressure monitoring, may be performed while you use Cardizem. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Use Cardizem with caution in the ELDERLY; they may be more sensitive to its effects, especially swelling of the ankles, feet, or hands; dizziness; and slow heartbeat.


• Cardizem should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Cardizem while you are pregnant. Cardizem is found in breast milk. Do not breast-feed while taking Cardizem.

Possible side effects of Cardizem:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; dizziness; facial flushing; headache; lightheadedness; tiredness; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); chest pain; fainting; fast, slow, or irregular heartbeat; fever, chills, or sore throat; hallucinations; mood or mental changes; personality changes; reddened, blistered, or swollen skin; severe or persistent dizziness, lightheadedness, nausea, or vomiting; shortness of breath; sudden weight gain; swelling of the feet, ankles, or hands; symptoms of liver problems (eg, dark urine, pale stools, yellowing of the skin or eyes); tender, bleeding, or swollen gums; unusual bleeding or bruising; unusual or persistent tiredness or weakness; vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Cardizem side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include confusion; difficulty breathing, especially when lying down; dizziness; drowsiness; fainting; lightheadedness, especially when standing; loss of consciousness; nausea; nervousness; slurred speech; unusual weakness; very slow heart rate.

Proper storage of Cardizem:

Store Cardizem at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Do not freeze. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Cardizem out of the reach of children and away from pets.

General information:

• If you have any questions about Cardizem, please talk with your doctor, pharmacist, or other health care provider.


• Cardizem is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Cardizem. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Cardizem resources

• Cardizem Side Effects (in more detail)
• Cardizem Use in Pregnancy & Breastfeeding
• Drug Images
• Cardizem Drug Interactions
• Cardizem Support Group
• 6 Reviews for Cardizem - Add your own review/rating

• Cardizem Prescribing Information (FDA)


• Cardizem Consumer Overview


• Cardizem Advanced Consumer (Micromedex) - Includes Dosage Information


• Diltiazem Prescribing Information (FDA)


• Cardizem CD Prescribing Information (FDA)


• Cardizem LA Prescribing Information (FDA)


• Cartia XT Prescribing Information (FDA)


• DILT-CD Prescribing Information (FDA)


• Dilacor XR Prescribing Information (FDA)


• Dilt-XR Prescribing Information (FDA)


• Diltia XT Prescribing Information (FDA)


• Diltiazem Hydrochloride Monograph (AHFS DI)


• Matzim LA Prescribing Information (FDA)


• Taztia XT Prescribing Information (FDA)


• Tiazac Prescribing Information (FDA)


• Tiazac Consumer Overview

Compare Cardizem with other medications

• Angina Pectoris Prophylaxis
• Atrial Fibrillation
• Atrial Flutter
• Heart Failure
• High Blood Pressure
• Raynaud's Syndrome
• Supraventricular Tachycardia